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1

Ion-exchange chromatography for the characterization of biopharmaceuticals

Fekete, Szabolcs, Beck, Alain, Veuthey, Jean-Luc, Guillarme, Davy

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

2

Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

Goyon, Alexandre, Excoffier, Melissa, Janin-Bussat, Marie-Claire, Bobaly, Balazs, Fekete, Szabolcs, Guillarme, Davy, Beck, Alain

Journal:

Journal of Chromatography B

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

3

Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future

Beck, Alain, D’Atri, Valentina, Ehkirch, Anthony, Fekete, Szabolcs, Hernandez-Alba, Oscar, Gahoual, Rabah, Leize-Wagner, Emmanuel, François, Yannis, Guillarme, Davy, Cianférani, Sarah

Journal:

Expert Review of Proteomics

Year:

2019

Language:

english

File:

PDF, 2.79 MB

english, 2019

4

Protocols for the analytical characterization of therapeutic monoclonal antibodies. II – Enzymatic and chemical sample preparation

Bobaly, Balazs, D’Atri, Valentina, Goyon, Alexandre, Colas, Olivier, Beck, Alain, Fekete, Szabolcs, Guillarme, Davy

Journal:

Journal of Chromatography B

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

5

Optimising the mutation screening strategy in Marfan syndrome and identifying genotypes with more severe aortic involvement

Stengl, Roland, Bors, AndrÃ¡s, Ãgg, Bence, PÃ³los, MiklÃ³s, Matyas, Gabor, MolnÃ¡r, MÃ¡ria Judit, Fekete, BÃ¡lint, CsabÃ¡n, DÃ³ra, Andrikovics, Hajnalka, Merkely, BÃ©la, Radovits, TamÃ¡s, Szabolcs, Z

Journal:

Orphanet Journal of Rare Diseases

Year:

2020

File:

PDF, 1.51 MB

2020

6

Validated UPLC method for the fast and sensitive determination of steroid residues in support of cleaning validation in formulation area

Szabolcs Fekete, Jenő Fekete, Katalin Ganzler

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

7

Fast and sensitive determination of Polysorbate 80 in solutions containing proteins

Szabolcs Fekete, Katalin Ganzler, Jenő Fekete

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2010

Language:

english

File:

PDF, 953 KB

english, 2010

8

Protocols for the analytical characterization of therapeutic monoclonal antibodies. III – Denaturing chromatographic techniques hyphenated to mass spectrometry

D'Atri, Valentina, Goyon, Alexandre, Bobaly, Balazs, Beck, Alain, Fekete, Szabolcs, Guillarme, Davy

Journal:

Journal of Chromatography B

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

9

Negative gradient slope methods to improve the separation of closely eluting proteins

Fekete, Szabolcs, Murisier, Amarande, Nguyen, Jennifer M., Lauber, Matthew A., Guillarme, Davy

Journal:

Journal of Chromatography A

Year:

2021

File:

PDF, 1.59 MB

2021

10

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase

Rodriguez-Aller, Marta, Guillarme, Davy, Beck, Alain, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 1.76 MB

english, 2016

11

Chromatographic, Electrophoretic and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals

Fekete, Szabolcs, Guillarme, Davy, Sandra, Pat, Sandra, Koen

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 2.88 MB

english, 2015

12

Protocols for the analytical characterization of therapeutic monoclonal antibodies. I – Non-denaturing chromatographic techniques

Goyon, Alexandre, D’atri, Valentina, Bobaly, Balazs, Wagner-Rousset, Elsa, Beck, Alain, Fekete, Szabolcs, Guillarme, Davy

Journal:

Journal of Chromatography B

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

13

Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?

D’Atri, Valentina, Pell, Reinhard, Clarke, Adrian, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Chromatography A

Year:

2018

Language:

english

File:

PDF, 910 KB

english, 2018

14

Mentalization across the psychosis spectrum

Fekete, Kata, Török, Edina, Makkos, Zoltán, Kelemen, Oguz, Csigó, Katalin, Kéri, Szabolcs

Journal:

Schizophrenia Research

Year:

2019

File:

PDF, 312 KB

2019

15

Analytical strategies for the characterization of therapeutic monoclonal antibodies

Szabolcs Fekete, Anne-Laure Gassner, Serge Rudaz, Julie Schappler, Davy Guillarme

Journal:

TrAC Trends in Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 752 KB

english, 2013

16

Childhood Leukaemia Incidence in Hungary, 1973–2002. Interpolation Model for Analysing the Possible Effects of the Chernobyl Accident

Szabolcs Török, Gábor Borgulya, Péter Lobmayer, Zsuzsanna Jakab, Dezsö Schuler, György Fekete

Journal:

European Journal of Epidemiology

Year:

2005

Language:

english

File:

PDF, 252 KB

english, 2005

17

Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates

Bobály, Balázs, Fleury-Souverain, Sandrine, Beck, Alain, Veuthey, Jean-Luc, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2017

Language:

english

File:

PDF, 986 KB

english, 2017

18

Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry

D’Atri, Valentina, Fekete, Szabolcs, Stoll, Dwight, Lauber, Matthew, Beck, Alain, Guillarme, Davy

Journal:

Journal of Chromatography B

Year:

2018

Language:

english

File:

PDF, 3.04 MB

english, 2018

19

High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling

Fekete, Szabolcs, Dong, Michael W., Zhang, Taylor, Guillarme, Davy

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2013

Language:

english

File:

PDF, 997 KB

english, 2013

20

Recent advances in chromatography for pharmaceutical analysis

D'Atri, Valentina, Fekete, Szabolcs, Clarke, Adrian, Veuthey, Jean-Luc, Guillarme, Davy

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

21

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products

Farsang, Evelin, Guillarme, Davy, Veuthey, Jean-Luc, Beck, Alain, Lauber, Matthew, Schmudlach, Andrew, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2020

Language:

english

File:

PDF, 2.98 MB

english, 2020

22

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system

Cusumano, Alessandra, Guillarme, Davy, Beck, Alain, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

23

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 1: alternative mobile phases and fine tuning of the separation

Farsang, Evelin, Murisier, Amarande, Horváth, Krisztián, Beck, Alain, Kormány, Róbert, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 484 KB

english, 2019

24

Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals

Goyon, Alexandre, Beck, Alain, Veuthey, Jean-Luc, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 568 KB

english, 2016

25

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: evaluation of recent stationary phases

Murisier, Amarande, Farsang, Evelin, Horváth, Krisztián, Lauber, Matthew, Beck, Alain, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 620 KB

english, 2019

26

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

Fekete, Szabolcs, Veuthey, Jean-Luc, Beck, Alain, Guillarme, Davy

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 3.54 MB

english, 2016

27

A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab

Duivelshof, Bastiaan L., Fekete, Szabolcs, Guillarme, Davy, D’Atri, Valentina

Journal:

Analytical and Bioanalytical Chemistry

Year:

2019

Language:

english

File:

PDF, 1.92 MB

english, 2019

28

Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography

Bobaly, Balázs, Beck, Alain, Veuthey, Jean-Luc, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 2.69 MB

english, 2016

29

Computer-assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy

Guichard, Nicolas, Fekete, Szabolcs, Guillarme, Davy, Bonnabry, Pascal, Fleury-Souverain, Sandrine

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 1.56 MB

english, 2019

30

Determination of size variants by CE-SDS for approved therapeutic antibodies: key implications of subclasses and light chain specificities

Wagner, Elsa, Colas, Olivier, Chenu, StÃ©phane, Goyon, Alexandre, Murisier, Amarande, Cianferani, Sarah, FranÃ§ois, Yannis, Fekete, Szabolcs, Guillarme, Davy, DâAtri, Valentina, Beck, Alain

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2020

File:

PDF, 2.41 MB

2020

31

Analysis of recombinant monoclonal antibodies by RPLC: Toward a generic method development approach

Szabolcs Fekete, Serge Rudaz, Jenő Fekete, Davy Guillarme

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

32

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

Fekete, Szabolcs, Beck, Alain, Fekete, Jenő, Guillarme, Davy

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

33

Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis

D’Atri, Valentina, Fekete, Szabolcs, Beck, Alain, Lauber, Matthew, Guillarme, Davy

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 860 KB

english, 2017

34

Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography

Fekete, Szabolcs, Grand-Guillaume Perrenoud, Alexandre, Guillarme, Davy

Journal:

Current Chromatography

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

35

Reliability of simulated robustness testing in fast liquid chromatography, using state-of-the-art column technology, instrumentation and modelling software

Kormány, Róbert, Fekete, Jenő, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

36

Characterization of cation exchanger stationary phases applied for the separations of therapeutic monoclonal antibodies

Fekete, Szabolcs, Beck, Alain, Guillarme, Davy

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

37

Facts and myths about columns packed with sub-3 μm and sub-2 μm particles

Szabolcs Fekete, Katalin Ganzler, Jenő Fekete

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

38

CLINICAL SOCIETY OF LONDON.

Fekete, Szabolcs, Guillarme, Davy

Journal:

Year:

1877

Language:

english

File:

PDF, 601 KB

english, 1877

39

Direct Identification of Rituximab Main Isoforms and Subunit Analysis by Online Selective Comprehensive Two-Dimensional Liquid Chromatography–Mass Spectrometry

Stoll, Dwight R., Harmes, David C., Danforth, John, Wagner, Elsa, Guillarme, Davy, Fekete, Szabolcs, Beck, Alain

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 1.96 MB

english, 2015

40

Orthogonal Middle-up Approaches for the Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High Resolution Mass Spectrometry

D'Atri, Valentina, Nováková, Lucie, Fekete, Szabolcs, Stoll, Dwight R, Lauber, Matthew Allen, Beck, Alain, Guillarme, Davy

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 1.19 MB

english, 2018

41

Impact of particle size gradients on the apparent efficiency of chromatographic columns

Codesido, Santiago, Rudaz, Serge, Veuthey, Jean-Luc, Guillarme, Davy, Desmet, Gert, Fekete, Szabolcs

Journal:

Journal of Chromatography A

Year:

2019

File:

PDF, 1.58 MB

2019

42

Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteins

DâAtri, Valentina, Murisier, Amarande, Fekete, Szabolcs, Veuthey, Jean-Luc, Guillarme, Davy

Journal:

TrAC Trends in Analytical Chemistry

Year:

2020

File:

PDF, 7.35 MB

2020

43

Investigating the use of unconventional temperatures in supercritical fluid chromatography

Losacco, Gioacchino Luca, Fekete, Szabolcs, Veuthey, Jean-Luc, Guillarme, Davy

Journal:

Analytica Chimica Acta

Year:

2020

File:

PDF, 1.93 MB

2020

44

Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed-phase stationary phases

Szabolcs Fekete, Serge Rudaz, Jean-Luc Veuthey, Davy Guillarme

Journal:

Journal of Separation Science

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

45

Evaluation of a new wide pore core–shell material (Aeris™ WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins

Szabolcs Fekete, Róbert Berky, Jenő Fekete, Jean-Luc Veuthey, Davy Guillarme

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 1.59 MB

english, 2012

46

New trends in reversed-phase liquid chromatographic separations of therapeutic peptides and proteins: Theory and applications

Szabolcs Fekete, Jean-Luc Veuthey, Davy Guillarme

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

47

Simultaneous determination of eight corticosteroids in bovine tissues using liquid chromatography–tandem mass spectrometry

Ádám Tölgyesi, Virender K. Sharma, Szabolcs Fekete, Dóra Lukonics, Jenő Fekete

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 389 KB

english, 2012

48

Reliability of computer-assisted method transfer between several column dimensions packed with 1.3–5μm core–shell particles and between various instruments

Kormány, Róbert, Fekete, Jenő, Guillarme, Davy, Fekete, Szabolcs

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 915 KB

english, 2014

49

Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials

Fekete, Szabolcs, Fekete, Jenő, Guillarme, Davy

Journal:

Journal of Chromatography A

Year:

2014

Language:

english

File:

PDF, 1005 KB

english, 2014

50

Simultaneous determination of polysorbate 20 and unbound polyethylene-glycol in protein solutions using new core–shell reversed phase column and condensation nucleation light scattering detection

Szabolcs Fekete, Katalin Ganzler, Jenő Fekete

Journal:

Journal of Chromatography A

Year:

2010

Language:

english

File:

PDF, 483 KB

english, 2010

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